A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal
at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture,
slowness of voluntary movements, and a masklike facial expression. Pathologic features
include loss of melanin containing neurons in the substantia nigra and other pigmented
nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus
coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE)
characterized by dementia in combination with varying degrees of parkinsonism. (Adams
et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Qualificatifs autorisés : DI / PS / IM / MI / DG / PP / RH / EN / ET / MO / EP / BL
/ CF / CN / DH / DT / TH / PX / UR / VI / VE / HI / CL / EC / EM / GE / NU / RT /
EH / PC / PA / ME / CO / SU1979(1963)
Informations sur la notice
Identifiant de la notice : 040755037
RCR créateur de la notice : 0001
Date de création : 23-09-1998
RCR dernier modificateur de la notice : 1999
Date de dernière modification : 26-11-2024 à 16 h 05