The erbB-2 gene is a proto-oncogene that codes for the erbB-2 receptor (RECEPTOR,
ERBB-2), a protein with structural features similar to the epidermal growth factor
receptor. Its name originates from the viral oncogene homolog (v-erbB) which is a
truncated form of the chicken erbB gene found in the avian erythroblastosis virus.
Overexpression and amplification of the gene is associated with a significant number
of adenocarcinomas. The human c-erbB-2 gene is located at 17q21.2
Note générale sur le champ d'application :
in titles & translations spell as erbB-2; GENES, ERBB-1 is also available