Gènes du récepteur du facteur de croissance épidermique
[Nom commun]
Gènes du récepteur du facteur de croissance épithélial
[Nom commun]
Proto-oncogènes c-erbB-1
[Nom commun]
Proto-oncogènes c-erbB1
[Nom commun]
Protooncogènes c-erbB-1
[Nom commun]
Gène erbB-1
[Nom commun]
Gènes erbB1
[Nom commun]
Informations
Note publique d''information :
The proto-oncogene c-erbB-1 codes for the epidermal growth factor receptor. Its name
originates from the viral homolog v-erbB which was isolated from an avian erythroblastosis
virus (AEV) where it was contained as a fragment of the chicken c-ErbB-1 gene lacking
the amino-terminal ligand-binding domain. Overexpression of erbB-1 genes occurs in
a wide range of tumors, commonly squamous carcinomas of various sites and less commonly
adenocarcinomas. The human c-erbB-1 gene is located in the chromosomal region 7p14
and 7p12
Note générale sur le champ d'application :
spell in titles & translations as erbB-1; GENES, ERBB-2 is also available