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Identifiant pérenne de la notice : 040834352Copier cet identifiant (PPN)
Notice de type FMeSH

Point d'accès autorisé

Antinéoplasiques alcoylants

Variantes de point d'accès

Alkylating Antineoplastic Agents
[Nom commun]
Alkylating Antineoplastic Drugs
[Nom commun]
Alkylating Antineoplastics
[Nom commun]
Antineoplastic Alkylating Agents
[Nom commun]
Antineoplastic Drugs, Alkylating
[Nom commun]
Antineoplastics, Alkylating
[Nom commun]
Alkylating Agents, Antineoplastic
[Nom commun]
Alkylating Drugs, Antineoplastic
[Nom commun]
Antineoplastic Alkylating Drugs
[Nom commun]
Drugs, Antineoplastic Alkylating
[Nom commun]
Agents anticancéreux alkylants
[Nom commun]
Anticancéreux alcoylants
[Nom commun]
Anticancéreux alkylants
[Nom commun]
Antinéoplasiques alkylants
[Nom commun]
Agents anticancéreux alkylants
[Nom commun]
Anticancéreux alcoylants
[Nom commun]
Anticancéreux alkylants
[Nom commun]
Antinéoplasiques alkylants
[Nom commun]

Informations

Note publique d''information : 
A class of drugs that differs from other alkylating agents used clinically in that they are monofunctional and thus unable to cross-link cellular macromolecules. Among their common properties are a requirement for metabolic activation to intermediates with antitumor efficacy and the presence in their chemical structures of N-methyl groups, that after metabolism, can covalently modify cellular DNA. The precise mechanisms by which each of these drugs acts to kill tumor cells are not completely understood. (From AMA, Drug Evaluations Annual, 1994, p2026)

Point d'accès autorisé parallèle

Antineoplastic Agents, Alkylating

Identifiants externes

Identifiant MeSH : mesD018906

Utilisation dans FMeSH

Qualificatifs autorisés : IP / IM / PK / TU / BL / CF / CS / CH / UR / RE / HI / AN / CL / EC / PD / ST / AD / SD / PO / AE / TO / ME96

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