An integrin that binds to a variety of plasma and extracellular matrix proteins containing
the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3
is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is
also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells,
where it is involved in angiogenesis and cell migration. Although often referred to
as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS,
VITRONECTIN)
Note générale sur le champ d'application :
do not confuse entry term VITRONECTIN RECEPTOR with VITRONECTIN RECEPTORS
Point d'accès autorisé parallèle
Integrin alphaVbeta3
Identifiants externes
Identifiant MeSH : mesD039302
Utilisation dans FMeSH
Qualificatifs autorisés : AD / AN / AI / BI / BL / CL / DF / DE / GE / HI / IM / IP
/ ME / PH / RE / TU / UL / CH / AG2003; use RECEPTORS, VITRONECTIN 1996-2002
Informations sur la notice
Identifiant de la notice : 073295523
RCR créateur de la notice : 7777
Date de création : 30-06-2003
RCR dernier modificateur de la notice : 4994
Date de dernière modification : 26-11-2024 à 13 h 59