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Note publique d'information : This book presents a comprehensive collection of detailed state-of-the-art exon skipping
and splices modulation protocols. Chapters detail 14 genetic diseases, AON-mediated
therapies, and CRISPR/Cas9-mediated gene editing therapies. Written in the highly
successful Methods in Molecular Biology series format, chapters include introductions
to their respective topics, lists of the necessary materials and reagents, step-by-step,
readily reproducible laboratory protocols, and tips on troubleshooting and avoiding
known pitfalls. Authoritative and cutting-edge, Exon Skipping and Inclusion Therapies:
Methods and Protocols aims to help researchers initiate the development of next-generation
therapies.