A system of metabolic interactions by products produced in the distal nephron of the
KIDNEY. These products include KALLIKREIN; KININS; KININASE I; KININASE II; and ENKEPHALINASE.
This system participates in the control of renal functions. It interacts with the
RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM to regulate BLOOD PRESSURE, generation of PROSTAGLANDINS,
release of VASOPRESSINS, and WATER-ELECTROLYTE BALANCE