Microtubule-associated proteins that are mainly expressed in neurons. Tau proteins
constitute several isoforms and play an important role in the assembly of tubulin
monomers into microtubules and in maintaining the cytoskeleton and axonal transport.
Aggregation of specific sets of tau proteins in filamentous inclusions is the common
feature of intraneuronal and glial fibrillar lesions (NEUROFIBRILLARY TANGLES; NEUROPIL
THREADS) in numerous neurodegenerative disorders (ALZHEIMER DISEASE; TAUOPATHIES)
Qualificatifs autorisés : IP / IM / PK / BI / PH / TU / AG / BL / CF / CS / DF / CH
/ DE / UR / RE / HI / AN / CL / EC / GE / PD / ST / AD / AI / SD / UL / PO / AE /
TO / ME1992; use TAU (NM) 1977-91
Informations sur la notice
Identifiant de la notice : 040816605
RCR créateur de la notice : 0001
Date de création : 23-09-1998
RCR dernier modificateur de la notice : 1999
Date de dernière modification : 26-11-2024 à 16 h 07